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In the context of injuries, reactive astrocytes exhibit plasticity, demonstrated by structural and functional characteristics common to aNSCs, including the expression of specific markers, and the ability to form neurospheres [ , , ]. DCs engage in an antigen-specific T cell differentiation by inducing deletion, anergy or regulation of regulatory T cells Treg [ ], followed by activation, proliferation, and differentiation to effector cells: the cytotoxic T- and helper T lymphocytes [ , ]. Hutter G et al.
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